Journal Sexual Medicine
In January issue of the Journal Sexual Medicine, the researchers have published the new study, measuring sexual hormone, linking globulin before and after the cessation of the spoken contraceptive pill. The Study solved that women, who used the spoken contraceptive pill can be subject to long-term problem from low values “unbound” potentially leading to continuing sexual, metabolic, and mental consequence of health.
The Sexual hormone, linking globulin, - a protein, which links giving this inaccessible for woman to physiological need. The Analysis shown this in woman with sexual dysfunction, elevated SHBG in “Oral Contraceptive Discontinued-Users” did not decrease in values corresponding to “Never-Users Spoken Contraceptive”. Thereby, as a result of chronic increasing in hormone, linking globulin level, consumers of the pill can be in risk for firm problems of health, including sexual dysfunction.
Spoken contraceptive was preferred method birth control because of their comfort of the use and high factor to efficiency. However, problem of sexual health of the women(woman) and hormonal problems is bound in some woman spoken contraceptive ironically. Now, there is data that spoken contraceptive pills can have lasting disadvantage effects on hormone.
The Study, in article named: “Influence Spoken Contraceptive in Polovom Hormone, linking Globulin and Androgennye Level: Retrospective Analysis in Woman with Sexual Dysfunction” published in Journal Sexual Medicine, involved 124 premenopausal womans with sexual complaint of health during more, than 6 months. Three groups of the womans were determined: I) 62 “Oral Contraceptive Continued-Users” were found on spoken contraceptive during more, than 6 months and were continued send him, ii) 39 “Oral Contraceptive Discontinued-Users” were found on spoken contraceptive during more, than 6 months and stopped them, and iii) 23 “Never-Users Spoken Contraceptive” never took spoken contraceptive. THE VALUES SHBG were compared in baseline (the groups I, ii and iii) while on spoken contraceptive (the groups I and ii), and well for 7 day half-life sexual hormone, linking globulin in 49-120 (the facility 80) days and more, than 120 (the facility 196) days following cessation spoken contraceptive (the group ii).
The Researchers solved that values SHBG in “Oral Contraceptive Continued-Users” were 4 once above than that in “Never-Users Spoken Contraceptive”. In spite of reduction in value SHBG after cessation of the spoken contraceptive use the pill, the level SHBG in “Oral Contraceptive Discontinued-Users” remained lifted when in contrast with “Never-Users Spoken Contraceptive”. This called on to question independently prolonged opening on complex estrogens spoken contraceptive generates the gene printing and raised expression of the gene SHBG in liver in some woman, who used spoken contraceptive.
Dr. Tank Claudia, endocrinologist in Denver, CO and leaden author of the analysis, noted that ” it is important for assigning spoken contraceptive to note on their potential sexual side effects patient such as, reduced desire, awakening, reduced lubrificant and raised sexual pain. Also if women present these complaints, she critical to acknowledge the reference between sexual dysfunction and spoken contraceptive and not to attribute these complaints to psychological reason solely.”
” Interesting observation was in that that use spoken contraceptive called on to changes to syntheses SHBG, which was not completely reversible in our time frame of the observation. This can conduct to more low level ‘unbound which is thought to be played main role on feminine sexual health. This will be important to conduct the long-term studies to see if these raised change SHBG constant,” added Dr. Panzer.
Dr. Andre Guay, Author of the analysis co-and Director of the Centre for Sexual Function/Endocrinology in Peabody, MA confirmed, which this analysis is an opening and that results were remarkable. The Conditions “Good while we have heard that subset of the womans, used spoken contraceptive agent suffers from reduced sexual of the drive,” Dr. Guay. “We know that birth control the pill will suppress both ovulation and also male hormones that ovaries to do on greater amount during medium third menstrual be repeated. SHBG LINKS consequently, these pills reduce feminine male accessibility of the hormone two separate mechanisms. Strangely Not so much womans.
“This work is a culmination 7 years observational studies in which we have noted on our practical person much womans with sexual dysfunction, which used spoken contraceptive but whose sexual and hormonal problems persisted in spite of stop birth control pills,” said Dr. Irwin Goldstein, urologist and senior author of the study. “There is aproximately 100 million womans worldwide who currently use spoken contraceptive so this obvious that more extended research studies - it is necessary. Spoken contraceptive was around over 40 years, but nobody previously did not look at long-term effects SHBG in these woman. The Big worries - that there is limited research measures in problem of sexual health of the women(woman) on contrast in investigatory measures in the other area of health of the women(woman) or in male sexual dysfunction even.”
To better value the area of the problem, spoken contraceptive were carried in USA in 1960 and were currently used for reversible pharmacological birth control over 10 million womans in USA, including 80% all American womans been born with 1945 and, to put it more exactly,, 27% age of the womans 15-44 and 53% age of the womans 20-24 years. Providing strong complex estrogen (ethinyl estradiol) and strong complex progesterone (for instance - norethindrone), very efficient contraception is reached reducing level FSH and LH, thereby reducing metabolic activity ovary including suppression to ovulations.
Several studies last 30 reported the negative effects spoken contraceptive on sexual function, including reduced sexual interest and awakening, suppression of the female sexual activity, reduced frequency sexual intercourse and sexual enjoyment. Androgeny such as, is an important modulator to sexual function. The Spoken contraceptive reduction, circulating level by direct prohibition production in ovaries and chosen by increase in liver syntheses sexual hormone relationship globulin, major, linking protein for gonadal steroid in circulations. The Combination these two ends mechanism to reduce level “unbound” or “free”.
This article is published in Journal Sexual Medicine.
The Journal Sexual Medicine publishes the multiprotocol main science and clinical study to define and understand the scientific base male and feminine sexual function and dysfunctions. As official journal International Society for Sexual Medicine, this provides healthcare professional in sexual medicine with essential educational contents and promotes exchange to scientific information generated from the main science and clinical study.
The International Society for Sexual Medicine (ISSM) was founded in 1982 for the reason promote the study and changing the knowledge for clinical object “weekness” for the whole international scientific society. The Society has over 2000 participants worldwide, with five times local society, which are joined ISSM: Africa Society Bay for Sexual Medicine, Asia Peace Society for Sexual Medicine, European Society for Sexual Medicine, Latino American Society for Sexual Medicine, and Sexual Society Medicine North America.
